ABSTRACT
Background: Obesity and overweight is a disorder of unusually increased body fat generally resulting from increased energy intake relative to energy expenditure and is a primary sustenance-related disorder globally. The extensive increase in its prevalence in current years and its association with reduced life expectancy has made obesity one of the most vital public health problems. The purpose of the study was to determine the relationship between serum lipid profile and blood pressure with body mass index (BMI). Material & Methods: A cross-sectional study was carried out in the Department of Physiology and Biochemistry, Rangpur Medical College, Rangpur from January 2013 to December 2013. A purposive sampling technique was followed. A total number of 90 people from 18 to 45 years old were included in the study, categorized into three groups, such as Group-A:(Control 30): Healthy subject of normal weight, Group-B:(Experimental 30): Healthy subject of overweight & Group-C(Experimental-30): Healthy subjects of obese. Verbal consent was taken before recruiting the study population. Completed data forms were reviewed, edited, and processed for computer data entry. The data analysis was performed using the “t” test, “r” test & Statistical Package for the Social Sciences (SPSS) Version 25.0. Results: In group A, the mean BMI of patients was 18.5-22.9, in group B mean BMI of patients was 23.0-24.9, and in group C, the mean BMI of people was 25.0 or greater. The mean ± SD serum LDL-C levels were 107.77 ± 26.720 mg/dl in group A and 134.70 ± 41.787 mg/dl in group B. There was a significant difference (p<0.001) between the two groups. The mean ± SD pulse pressure levels were 38 ± 6.644 mmHg in group A and 41.67 ± 11.167 mmHg in group B. There was no significant difference (p>0.05) between the two groups. Serum total cholesterol levels were positively correlated in groups A & B but the relationship of serum total cholesterol levels was statistically significant in groups A and B. Blood pressure levels were positively correlated in groups A &C but the relationship was statistically non-significant. Conclusion: In this current content, it is difficult to define the specific mechanism involved for significantly higher serum total cholesterol, serum triglyceride, and serum LDL-C levels and non-significantly lesser serum HDL-C levels in overweight & obese people and also non-significantly higher blood pressure in overweight people but significantly higher blood pressure in obese subjects.
ABSTRACT
Background: Tobacco industry workers are exposed to tobacco dust and smoke in their work places. Usually they have varying degree of impaired pulmonary functions, but the level of awareness about this occupational hazard among the tobacco industry workers and authorities are limited. Objective: The present study was conducted to observe the effects of exposure to tobacco dust and smoking on FVC, FEV1 and FEV1%. Methods: This cross-sectional study was carried out in the Department of Physiology, Rangpur Medical College, Rangpur, from July 2008 to June 2009 on 50 apparently healthy male smoker (Group B) and 40 non-smoker (Group C) tobacco industry workers with age range 20 to 45 years. For comparison,50 age and body surface area matched apparently healthy male non-smoker non-tobacco workers were also studied as Control(group A). The study groups were selected from different tobacco industries of Rangpur district and control group were selected from the surrounding community who belonged to lower socioeconomic condition. Pulmonary function parameters were measured by digital spirometer. Statistical analysis was done by unpaired‘t’ test . Results: Smoker tobacco workers had significantly lower percentage of predicted values of FVC, FEV1 and FEV1% than control subjects (p <0.001). In addition, they had significantly lower values of FEV1 and FEV1% than non-smoker tobacco workers (p <0.01). Conclusion: Pulmonary functions may be impaired in smoker tobacco workers.